This picture is from episode 1 of the new Captain America mini series Winter Soldier – The Bitter March. The five part mini-series is scheduled to begin in February before the Winter Soldier movie opens on April 4, 2014.
Set in 1966, Hydra has a secret Nazi weapon and the Soviets and S.H.I.E.L.D. are battling to gain control of it during their cold-war duel. In particular, the Winter Soldier is a super soldier who has been brain-washed to work for the Soviets. He is up against Nick Fury. The outcome is supposed to have a significant impact on Captain America in the future.
Marvel is a little coy about details at this point, but more will likely be provided as the release date nears.